A
key to the abbreviations used and information on the different
anti-malarial drug regimens can be found below the main tables
Malaria
endemic countries in Asia
Note: In
this map, countries with areas endemic for malaria are shaded completely
even if transmission occurs
in only part of that country. For more specific within country information,
see the guidelines below.
Dengue
Risk in Asia
Geographic
Distribution of Japanese Encephalitis
Disease Risks
in the Indian Subcontinent
Bangladesh,
Bhutan, India, Maldives, Nepal, Pakistan, Sri Lanka.
Borneo (see
Indonesia and Malaysia), Brunei Darussalam, Burma (see Myanmar),
Cambodia, China (including Tibet), East Timor, Hong Kong (see China),
Indonesia (including Bali and southern Borneo), Japan, Korea, Laos,
Macao (see China), Malaysia (Peninsular Malaysia and northern Borneo,
including Sarawak and Sabah), Mongolia, Myanmar (formerly Burma),
the Philippines, Singapore, Taiwan, Thailand, Tibet (see China),
Vietnam.
Vaccination is mandatory
and a certificate of vaccination is required for entry.
C
A certificate
of vaccination may be required if entering from an endemic
country, (except for children <1 year old).
R
Vaccination is recommended
for the country but no evidence is required for entry.
L
Long Term. Vaccination recommended
for travellers staying in endemic areas for 3 months
or more. Except Japanese B Encephalitis if longer than
1 month.
COUNTRY
MALARIA
REGIMEN
YEL
HEP
A
TYP
TET
POL
MEN
ENC
DIP
RAB
HEP
B
Afghanistan Malaria risk below 2000 metres
from May to Nov
2
C
R
R
R
R
-
-
L
L
L
Armenia Malaria risk in some villages
in the Ararat Valley, mainly in the Masis district,
from June to October - Regimen 3. No risk in the main
tourist areas Regimen 4.
3/4
-
R
R
R
R
-
-
L
L
L
Azerbaijan Limited malaria risk from
June to October in the south border area and Khachmas.
Also in lowland areas, mainly in the areas between the
Kura and the Arax rivers.
3
-
R
R
R
R
-
-
L
L
L
Bahrain No malaria risk
-
-
R
R
R
R
-
-
L
L
L
Bangladesh High malaria risk in the south
east and Chittagong Hill Tracts - Regimen 1. All other
areas - Regimen 2.
No risk in Dhaka city - Regimen 4.
1/2/4
-
R
R
R
R
-
L
L
L
L
Bhutan Risk of Malaria is only
present in the southern districts of Bhutan.
2
C
R
R
R
R
R
-
L
L
L
Brunei No malaria risk
-
C
R
R
R
R
-
L
L
L
L
Cambodia Malaria risk is present throughout
the country including the areas around the famous temple
complex of Angkor Wat near Siem Reap - Regimen 1.
Risk
is minimal in the capital city
1/4
C
R
R
R
R
-
L
L
L
L
Phnom
Penh, the nearby Mekong river
delta and in the rice growing areas around the large
inland lake of Tonle Sap - Regimen 4.
Note:
There is mefloquine resistance present in western provinces
& the border with Thailand.
China Urban and densely populated
areas are normally malaria free.
Serious risk of malaria in China is now confined to
a few areas not normally visited by package tourists
or business travellers but may be visited by backpackers
or voluntary workers.
Risk
is present only on Hainan island, in Yunnan province
and sporadically in Guangxi province - Regimen 1.
1/3/4
C
R
R
R
R
-
L
L
L
L
Less
serious malaria occurs in a few isolated areas in the
'flood' plains of the Yangtze (Chang Jiang) and Yellow
(Huang He) rivers - specifically within
the provinces of Fujian, Guangxi, Guangdong, Guizhou,
Sichuan and Xizang (along the valley of the Zangbo river).
Isolated
cases occasionally occur in other parts of the country
Regimen 3.
All other regions including the main tourist areas -
very little risk, avoid mosquito bites - Regimen 4.
Georgia Malaria risk in some areas
located in the south eastern part of the country from
July to October.
3
-
R
R
R
R
-
-
R
L
L
Hong
Kong Very low malaria risk - avoid
mosquito bites.
4
C
R
R
R
R
-
L
L
L
L
India Malaria risk exists in all Indian
states below 2000m especially in rural areas and Goa
particularly areas north of Panaji - Regimen 2. - See
note on Goa
Low risk in the southern states of Kerala, Tamil Nadu,
Karnataka, and southern Andhra Pradesh including Hyderabad
and the city of Mumbai - Regimen 3.
Low risk also in the northern states of Rajasthan, Uttar
Pradesh, Punjab and the cities of Delhi and Aggra.
1/2/3/4
C
R
R
R
R
R
L
L
L
L
In
these low risk areas it may not be necessary to take
antimalarial medication especially if travel is restricted
to urban areas - Regimen 3 or 4.
Very low to no risk in northern mountain states including
the high altitude Himalayan states of Jammu and Kashmir,
Himachal Pradesh and Sikkim - Regimen 4.
High
risk in the eastern state of Assam where resistance
to chloroquine has been reported - Regimen 1.
Indonesia
including Bali There is a malaria risk throughout
Indonesia all year round but the risk is small in all
large cities like Jakarta and the tourist resorts on
the islands of Bali and Java - Regimen 4.
1/2/4
C
R
R
R
R
-
L
L
L
L
Travellers
should be aware that the malaria risk is substantial in
islands close to Bali and Java which may be visited on
excursions e.g. Lombok
and
West Papua (previously Irian Jaya) and East Timor - Regimen
1
All other areas except cities - Regimen 2.
Iran Malaria
risk is minimal in areas north of the Zagros mountains
and in western and south-western regions during the
summer months. A more substantial risk is present from
March to November in the south-eastern provinces of
Sistan - Baluchestan, Hormozgan and Kerman.
2
-
R
R
R
R
-
-
L
L
L
Iraq Malaria
risk in northern rural areas and Basrah province in
the south from May to November.
2
C
R
R
R
R
-
-
L
L
L
Israel No malaria
risk
-
-
R
R
R
R
-
-
L
L
L
COUNTRY
MALARIA
REGIMEN
YEL
HEP
A
TYP
TET
POL
MEN
ENC
DIP
RAB
HEP
B
Japan No
malaria risk
-
-
-
-
R
R
-
L
L
L
L
Jordan No
malaria risk
-
C
R
R
R
R
-
-
L
L
L
Kazakhstan No
malaria risk
-
C
R
R
R
R
-
-
L
L
L
Korea
(north) No
malaria risk
-
-
R
R
R
R
-
L
L
L
L
Korea (south) No
malaria risk
-
-
R
R
R
R
-
L
L
L
L
Kuwait No
malaria risk
-
-
R
R
R
R
-
-
L
L
L
Kyrgystan No
malaria risk
-
-
R
R
R
R
-
-
L
L
L
Laos Malaria
risk in the whole country - Regimen 1, except Vientiane
- Regimen 4.
1/4
C
R
R
R
R
-
-
L
L
L
Lebanon No
malaria risk
-
C
R
R
R
R
-
-
L
L
L
Malaysia Malaria
precautions are essential.
In western peninsular Malaysia the risk is confined to
the Taman Negara National Park (around and east of Mount
Tahan) and some remote inland forested areas not normally
visited by tourists.
In the eastern Malaysian provinces
1/2/4
C
R
R
R
R
-
L
L
L
L
of Sabah and Sarawak and on the island of Borneo malaria
is widespread - Regimen 1.
However
coastal urban areas of Sarawak are considered minimal
risk - Regimen 2.
All
other areas including Kuala Lumpur, Penang & the developed
tourist areas of the Cameron Highlands are not normally
at risk - regimen 4.
Maldives No malaria
risk but always take anti-mosquito bite measures.
4
C
R
R
R
R
-
-
L
L
L
Mongolia No malaria
risk but always take anti-mosquito bite measures.
4
-
R
R
R
R
R
-
L
L
L
Myanmar
(Burma) Malaria
risk is present in all areas below 1000m but risk is less
in Yangon and Mandalay - Regimen 1. (Mefloquine resistance
on Thai border areas).
1
C
R
R
R
R
-
-
L
L
L
Nepal Malaria
risk in areas below 1200 metres e.g. the Chittwan National
Park - Regimen 2. All other areas including Kathmandu
- Regimen 4.
2/4
C
R
R
R
R
R
L
L
L
L
Oman Malaria
risk in remote areas in the north including Musandam province
- regimen 2. Muscat is considered malaria free.
2
C
R
R
R
R
-
-
L
L
L
Pakistan Malaria
risk is present in the whole country in areas below 2000m
(i.e. everywhere except in the Himalayas in the far north)
and more so in the hotter months and after the monsoon
rains (May - October) - Regimen 2.
2
C
R
R
R
R
-
L
L
L
L
COUNTRY
MALARIA
REGIMEN
YEL
HEP
A
TYP
TET
POL
MEN
ENC
DIP
RAB
HEP
B
Philippines Malaria risk present below 600m in rural
areas - Regimen 2.
No risk in the island provinces of Aklan, Bilaran, Bohol,
Camiguin, Catanduanes,
Risk is small in the plains to the north
of Manila and other major cities - Regimen 4.
Qatar No malaria
risk
-
-
R
R
R
R
-
-
L
L
L
Russia No malaria
risk
-
-
R
R
R
R
-
-
R
L
L
Saudi
Arabia Malaria
risk exists throughout the year in most of the Southern
Region and in certain rural areas of the Western region
- Regimen 2.
No risk in Mecca or Medina or in the high altitude areas
of Asir Province - Regimen 4.
2/4
C
R
R
R
R
R
xM*
-
L
L
L
*meningococcal
vaccination is now mandatory for pilgrims on Hajj to Mecca,
otherwise recommended for stays of one month or more.
Singapore No malaria
risk.
-
C
R
R
R
R
-
-
L
-
L
Sri
Lanka Malaria
risk in the whole country - Regimen 2.
Colombo and the coastal resorts of Galle, Nuwara Eliya
and Kalutara, no risk of malaria but bite avoidance is
recommended - Regimen 4.
2/4
C
R
R
R
R
-
L
L
L
L
Syria Malaria
risk exists in northern border areas from May to October.
3
C
R
R
R
R
-
-
L
L
L
Taiwan No malaria
risk
-
-
R
R
R
R
-
-
L
L
L
Tajikistan Malaria
risk exists from June - October, particularly in southern
border areas (Khatlon region) and in some central (Dushanbe),
western (Gorno-Badakhshan), and northern (Leninabad) areas.
3
-
R
R
R
R
-
-
L
L
L
Thailand Malaria
risk is present throughout the year but mainly in rural
and forested areas near the borders with Myanmar (Burma),
Laos and Cambodia - Regimen 1.
Since mefloquine resistance is now common in these areas,
Malarone OR doxycycline is usually advised.
1/4
C
R
R
R
R
-
L
L
L
L
There
is very little risk in the central parts of the country
and along the coastal road and train routes from the
Malaysian/Thai peninsular into central Thailand - Regimen
4.
The
risk is very small in major cities such as Bangkok, Chiang
Mai, Chiang Rai and the tourist resorts of Pattaya, Phuket,
the River Quai bridge area and the Ko Samui islands -
Regimen 4.
Turkey Risk
occurs from March to November, mainly in the south-eastern
part of the country; Antalya, Side and Alanya, the east
coast, south east Anatolia the plain around Adona, the
Syria and Iraq borders and in Amikova and Cukurova Plain
- Regimen 3
3/4
-
R
R
R
R
-
-
L
L
L
There
is no malaria risk in the main tourist areas in the west
and south-west of the country. No risk west of Antalya
- Regimen 4.
Turkmenistan Malaria
risk in the south-east, mainly Mary district, from June-October.
3
-
R
R
R
R
-
-
L
L
L
United
Arab Emirates There
is a very limited malaria risk in some valleys in the
east and in the northern rural areas of the country -
Regimen 2.
There is not normally any risk in Abu Dhabi and the cities
of Dubai, Sharjah, Ajman and Umm al Qaiwainrisk - Regimen
4.
2/4
-
R
R
R
R
-
-
L
L
L
Uzbekistan No malaria
risk
-
-
R
R
R
R
-
-
L
L
L
Vietnam Malaria
risk is present in the whole country - Regimen 1.
Excluding urban centres such as Ho Chi Min City (Saigon)
and Hanoi, the Red River delta and the coastal plain areas
of central Vietnam north of Nha Trang - Regimen 4.
1/4
C
R
R
R
R
-
L
L
L
L
Yemen Malaria
risk exists throughout the year but mainly from September
to February, in the whole country below 2000m. Malaria
risk on Socotra Island - Regimen 2.
There is no risk in Sana'a city. In Aden and the airport
perimeter the risk is minimal - Regimen 4.
2/4
-
R
R
R
R
-
-
L
L
L
YEL
Yellow Fever
HEP
A
Hepatitis A
TYP
Typhoid
TET
Tetanus
POL
Polio
MEN
Meningitis
ENC
Jap. B Encephalitis
DIP
Diphtheria
RAB
Rabies
HEP
B
Hepatitis B
M
Vaccination is mandatory
and a certificate of vaccination is required for
entry.
C
A certificate
of vaccination may be required if entering from
an endemic country, (except for children <1 year
old).
R
Vaccination is recommended
for the country but no evidence is required for
entry.
L
Long Term. Vaccination
recommended for travellers staying in endemic
areas for 3 months or more. Except Japanese B
Encephalitis if longer than 1 month.
The information supplied
is derived from a number of reliable sources and is
compared and compiled into the alphabetical lists found
on this web site.
Countries requiring malaria prophylaxis should be
regarded as being at risk all year round and
you should also assume that the whole country
is at risk unless otherwise indicated. Themalaria
regimen is therecommended regimen for a country.
Use of the incorrect regimen may not provide adequate
cover.
When there are two different regimens
for the same country, they are area specific. Read the
text to find out which regimen is suitable for the area
you require.
Where regimen 1 is indicated there is Chloroquine
resistance in that region and it is very likely to be
the Falciparum malaria which is the most serious form
of the disease. In this instance it is vitally important
that travellers take adequate prophylaxis.
Remember:- No prophylaxis is 100% effective but
not taking anti-malarials where they are indicated will
put you at greater risk should you get the disease.
Remember - Malaria is a killer!
The Different Drug Regimens
Regimen
1
Mefloquine one 250mg tabletweekly. OR
Doxycycline one 100mg capsule daily. OR
Malarone one tablet daily.
No
prophylactic tablets required but anti mosquito measures
should be strictly observed: Avoid
mosquito bites by covering up with clothing such as long
sleeves and long trousers especially after sunset, using
insect repellents on exposed skin and, when necessary,
sleeping under a mosquito net.
.
Proguanil
100mg tablets are
supplied as Paludrine Tablets
Chloroquine
150mg tablets are
supplied as Nivaquine or Avloclor Tablets
Mefloquine
250mg tablets are
supplied as Lariam Tablets
Malarone
is a
combination of Atovaquone 250mg and Proguanil
100mg
Length of Prophylaxis
Chloroquine, Proguanil & Maloprim
Start
one week before travel, throughout your stay in
an endemic area and continue for four weeks after
return.
Mefloquine (Lariam)
Start
two and a half weeks before travel, throughout
your stay in an endemic area and continue for four
weeks after return.
Doxycycline
Start two days before travel, throughout
your stay in an endemic area and continue for four
weeks after return.
Malarone
Start
two days before travel, throughout your stay in
an endemic area and continue for one week after
return.
IMPORTANT!
Take the
tablets absolutely regularly, preferably with or after
a meal.
Long Term
Use of Anti-Malaria Drugs
Chloroquine
May be
taken for periods exceeding five years.
Paludrine
May be
taken for periods exceeding five years.
Maloprim
Can be
taken for periods up to one year.
Mefloquine
Can be
taken for periods up to one year.
Doxycycline
Can be
taken for periods up to six months.
Malarone
Can be
used for travel periods up to one year.
Compatibility of Anti-Malaria Drugs
Pregnancy
Breast
Feeding
Epilepsy
Psoriasis
Altitude
Scuba
Diving
Chloroquine
OK
OK
NO
NO
OK
OK
Paludrine
OK
OK
OK
OK
OK
OK
Mefloquine
OK*
NO
NO
OK
NO
NO
Doxycycline
NO
NO
OK
OK
OK
OK
Malarone
NO
NO
OK
OK
OK
OK
*
These drugs are not suitable during the first trimester
of pregnancy.
Childrens' Dosages: Calculate
the dose by weight rather than by age if possible
Age/Weight
Chloroquine
(once weekly)
Proguanil
(once daily)
Mefloquine
(once weekly)
Doxycycline
(once daily)
Malarone
(once daily)
0
- 12 weeks
under 6kg
1/4
tablet
1/4
tablet
-
-
-
3
- 12 months
6 - 10kg
1/2
tablet
1/2
tablet
1/4
tablet
-
-
1
- 3 years
10 - 16kg
3/4
tablet
3/4
tablet
1/4
tablet
-
1
child's
tablet
4
- 7 years
16 - 25kg
1
tablet
1
tablet
1/2
tablet
-
1
child's
tablet
8
- 12 years
25 - 45 Kg
11/2
tablets
11/2
tablets
3/4
tablet
-
2
child's
tablets
13
years and over
45kg and over
2
tablets
2
tablets
1
tablet
1
capsule
1
adult
tablet
The
above dosages are based upon the guidelines issued by
the Advisory Committee on Malaria Prevention.
Adult
Dosages
Regimen
Dose
for
Chemoprophylaxis
Usual
amount
per tablet (mg)
Areas
without drug resistance:
Chloroquine
Proguanil
2
tablets weekly
2
tablets daily
150mg
(base)
100mg
Areas
of little chloroquine resistance (poorly effective where
marked resistance):
Chloroquineplus Proguanil
2
tablets weekly
2 tablets daily
150mg
(base)
100mg
Areas
of chloroquine resistant P. falciparum:
Mefloquine
Doxycycline
Malarone
(atovaquone & proguanil)
1
tablet weekly
1
tablet/capsule daily
1
tablet daily
250mg
(228 in USA)
100mg
250mg
atovaquone &
100mg proguanil
Malaria
in China
Malaria
in India
Malaria
prevention guidelines for travellers to Goa
In
early 2007 a number of cases of Plasmodium falciparum
malaria were reported in UK travellers returning from
Goa. None were known to have taken malaria chemoprophylaxis.
During the same period, a number of cases were also
seen in other European travellers.
This has resulted in the guidelines being revised to
recommending chemoprophylaxis for all travellers visiting
Goa.
The
current recommendations for travellers visiting Goa
are as follows:
Malaria
chemoprophylaxis is recommended to those travellers
who will be visiting Goa , particularly areas north
of Panaji. The recommended chemoprophylaxis is chloroquine
plus proguanil. Alternatives are mefloquine, Malarone,
or doxycycline.
All travellers to Goa should also use mosquito bite
avoidance measures.
All
travellers should seek medical attention promptly if
they become unwell whilst away or after returning and
inform their doctor that they have been in a malarious
area. The healthcare worker should consider malaria
in every ill patient who has recently returned from
the tropics; for those with a fever, the illness should
be considered to be malaria until proven otherwise.